What is Dysautonomia?
Dysautonomia is characterized by degeneration of neurons in the autonomic ganglia with associated failure of sympathetic and parasympathetic functions. Neurons are diminished or absent in the ganglia of affected dogs and replaced by gliosis. There is little inflammation present.
according to Dennis P. O’Brien DVM Phd (University of Missouri) Dysautonomia has been diagnosed primarily in young adult dogs (median age 14 months with a range from 8 weeks to 10 years of age). Although Labrador retrievers were slightly over-represented, a wide variety of breeds have been affected. The most common presenting complaints in affected dogs have been dysuria, regurgitation, purulent nasal discharge, photophobia, anorexia, and weight loss . The duration of clinical signs averaged about 2 weeks

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